5 of the Best Supplements for Energy

Have you been feeling tired lately and don’t know how to improve your energy? You could benefit from energy support! At Keystone Compounding Pharmacy, we have a great collection of supplements designed to help improve your energy levels, as well as help other aspects of your health. Learn more about 5 of our best supplements for energy below:

1. Mito-Fuel: The Complete Multivitamin to be Completely Energized and Protected From Cell Damage

Mitochondria are the "powerhouse" of the cell! They produce energy (ATP) for cell functions. Factors like poor sleep, diet, and medications can deplete mitochondrial energy. Mito-fuel is the complete multivitamin that gives your cells the components required to improve energy production at a cellular level, reduce inflammation, and protect the mitochondria, the powerhouse of the cell.

Free radicals, produced naturally in the body and from environmental factors, can damage cells and impair their function. Antioxidants like those found in Mito-Fuel are essential in combating this damage. Mito-Fuel contains Alpha Lipoic Acid (ALA), a powerful antioxidant that works in all cells to boost mitochondrial energy production, converting glucose into ATP for higher energy levels and less fatigue. Paired with N-Acetyl Cysteine (NAC), which supports overall cell health, and Acetyl L-carnitine, which helps convert fat into energy, this trio not only boosts energy but also protects and strengthens your cells, enhancing both physical and mental clarity. Mito-Fuel combines essential micronutrients and phytonutrients like resveratrol to support mitochondrial health, boost energy production, protect the cell against oxidative stress helping to prevent chronic inflammation, and they protect the cell from DNA damage all so your cells can be protected and efficient while filling your energy stores.

2. CoQ Synergy: A Boost For Your Energy and Your Heart

CoQ Synergy combines Coenzyme Q10 (Ubiquinone) and TrueBroc® broccoli seed extract. These powerful compounds work synergistically to enhance your health on multiple levels, from energy production to detoxification and cellular protection. Here’s why they’re must-haves:

Coenzyme Q10 (Ubiquinone): Your Energy Powerhouse

CoQ10 is a naturally occurring antioxidant found in every cell of your body, where it plays a crucial role in producing energy (ATP) in the mitochondria. When your body has enough CoQ10, you’ll feel the difference in your energy levels, mental clarity, and even heart health.

• Energy Boost: Coenzyme Q10 is essential for converting nutrients into energy, making it a great supplement to fight fatigue and boost physical performance.
• Heart Health Support: Ubiquinone is vital for cardiovascular health, supporting the heart’s energy needs and maintaining healthy blood pressure levels.
• Antioxidant Protection: As a powerful antioxidant, CoQ10 protects your cells from damage caused by free radicals, helping slow the aging process and reduce inflammation.
• Brain Health: CoQ10 keeps your brain functioning at its best by protecting brain cells from oxidative damage and ensuring efficient energy production, improving mental sharpness.

TrueBroc® is Rich in Glucoraphanin: The Detox & Cellular Health Superhero

Glucoraphanin, a precursor to sulforaphane found in broccoli and other cruciferous vegetables, offers remarkable detoxifying and antioxidant benefits. Once it converts into sulforaphane in your body, it works wonders to protect your cells and improve your metabolic health.

• Detoxification Support: Sulforaphane activates detoxification enzymes, helping your body eliminate harmful toxins from the environment, improving overall health and resilience.
• Antioxidant Defense: Glucoraphanin boosts your body’s natural antioxidant defenses, protecting cells from oxidative stress and inflammation, which are linked to aging and chronic diseases.
• Cellular Protection: Sulforaphane promotes healthy cell function, aiding in normal cell growth and reducing the risk of cancer by removing damaged cells.
• Metabolic Health: Studies show glucoraphanin helps reduce oxidative stress and inflammation, supporting weight management, insulin sensitivity, and metabolic function.

CoQ10 and TrueBroc® Together in CoQ Synergy

When combined, CoQ10 and glucoraphanin offer an all-encompassing boost to your energy levels, cellular health, and overall vitality. CoQ10 fuels your body with energy, while glucoraphanin in TrueBroc® detoxifies and protects your cells, ensuring you stay energized, sharp, and resilient. Together, they offer:

• Higher energy levels and less fatigue
• Powerful antioxidant protection against aging and disease
• Enhanced heart, brain, and metabolic health

3. Super B Complex: B Vitamins Critical to Many Body Functions

Full Range of B Vitamins Plus Two Unique Forms of Vitamin B

Getting a full range of B vitamins, including hydroxocobalamin chloride and adenosylcobalamin, provides numerous essential benefits that go beyond just boosting energy. All of these are found in our Super B Complex. Each B vitamin plays a unique role in supporting key body functions. For example, Vitamin B1 (thiamine) aids in breaking down glucose for energy, which is critical for proper nervous system and brain function. Vitamin B2 (riboflavin) helps convert food into energy while also supporting healthy skin and eye function. Vitamin B3 (niacin) is known for improving circulation and cholesterol levels, while Vitamin B6 (pyridoxine)** helps regulate mood and sleep patterns.

When you include specialized forms of B12 like hydroxocobalamin chloride, you’re ensuring a more effective absorption of this vital nutrient. Hydroxocobalamin acts aids in red blood cell formation and the prevention of anemia. This form makes it a long-acting reservoir which means it is especially beneficial for individuals who have trouble absorbing traditional B12 forms or are looking for long-lasting support.

Adenosylcobalamin, another form of B12, is essential for mitochondrial health. As the active mitochondrial version of B12, it directly fuels energy production within the cells, making it crucial for people seeking sustained energy levels throughout the day. This version of B12 is also key for enhanced physical performance and recovery.

Incorporating these B vitamins alongside hydroxocobalamin chloride and adenosylcobalamin in our Super B Complex ensures comprehensive support for your body's metabolic processes, energy production, cognitive function, and overall health.

4. Essential Mag: Easy on the Stomach Magnesium That Improves Mental and Physical Wellbeing

Magnesium is an essential mineral involved in over 300 enzymatic reactions in the body, many of which are related to energy production, muscle function, and communication of nerves to nerves. It plays a role in muscle relaxation, which can help prevent muscle cramps and fatigue. Magnesium deficiency is often linked to fatigue, muscle weakness, and poor energy levels. Magnesium deficiency is a common problem, and supplementing with magnesium can improve energy levels and overall well-being.

Here, we explore three bioavailable forms of magnesium that increase energy and are easier on the stomach. A plus is our brand, Essential Mag, formulates three highly absorbable forms of magnesium all together in one supplement, so they are easier to take. These three forms of magnesium are Di-Magnesium Malate, which supports ATP production and reduces muscle fatigue; Magnesium Citrate, known for boosting energy and relieving muscle cramps by quickly replenishing magnesium levels; and Magnesium Glycinate, which promotes restful sleep and improves overall energy. Since the magnesium glycinate is a chelated form in our supplement it allows for easier stomach absorption. Supplementing with these forms of magnesium can enhance energy levels, reduce fatigue, and improve well-being.

5. HPA Calm: Calm Your Mood and Reduce Your Stress

The ingredients in HPA Calm, including Relora (a blend of Magnolia officinalis and Phellodendron amurense barks), holy basil, and L-theanine, work together to help reduce stress and its related impacts on the body. Relora has been shown to lower cortisol levels, helping to mitigate stress-related weight gain and improve mood. Holy basil is an adaptogenic herb known for its ability to balance stress hormones, improve mental clarity, and promote overall resilience to stress. L-theanine, an amino acid found in tea, promotes relaxation without drowsiness and helps to maintain heart rate variability. Together, these ingredients help regulate stress, improve heart health, and support healthy weight management.

If you’re in need of an energy boost, these 5 supplements are a great place to start. Take a look at all of our supplements for energy and get ready to feel more energized!

References

1. Baechler, B. J., Nita, F., Jones, L., & Frestedt, J. L. (2009). Novel Liquid Multi-Phytonutrient Supplement Demonstrates DNA-Protective Effects. Plant Foods for Human Nutrition (Dordrecht), 64(2), 81–85. https://doi.org/10.1007/s11130-009-0107-2
2. Cloyd, J. (2024, July 24). Magnesium glycinate vs. Citrate: Which should you take?. Rupa Health. https://www.rupahealth.com/post/magnesium-glycinate-vs-citrate-which-should-you-take
3. Evans, M., McDonald, A. C., Xiong, L., Crowley, D. C., & Guthrie, N. (2021). A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave®l-Theanine on Stress in a Healthy Adult Population. Neurology and Therapy, 10(2), 1061–1078. https://doi.org/10.1007/s40120-021-00284-x
4. Lobo, V., Patil, A., Phatak, A., & Chandra, N. (2010). Free radicals, antioxidants and functional foods: Impact on human health. Pharmacognosy reviews, 4(8), 118–126. https://doi.org/10.4103/0973-7847.70902
5. Maggini, S., Óvári, V., Ferreres Giménez, I., & Pueyo Alamán, M. G. (2021). Benefits of micronutrient supplementation on nutritional status, energy metabolism, and subjective wellbeing. Nutrición Hospitalaria: Organo Oficial de La Sociedad Española de Nutrición Parenteral y Enteral, 38(Spec No2), 3–8. https://doi.org/10.20960/nh.03788
6. Mayo Foundation for Medical Education and Research. (2022, June 7). Niacin to improve cholesterol numbers. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/niacin/art-20046208
7. Mizuno, K., Sasaki, A. T., Watanabe, K., & Watanabe, Y. (2020). Ubiquinol-10 Intake Is Effective in Relieving Mild Fatigue in Healthy Individuals. Nutrients, 12(6), 1640. https://doi.org/10.3390/nu12061640
8. Moon, J. M., Ratliff, K. M., Hagele, A. M., Stecker, R. A., Mumford, P. W., & Kerksick, C. M. (2021, December 28). Absorption kinetics of berberine and dihydroberberine and their impact on glycemia: A randomized, controlled, crossover pilot trial. MDPI. https://doi.org/10.3390/nu14010124
9. Alpha-lipoic acid. Mount Sinai Health System. (n.d.-c). https://www.mountsinai.org/health-library/supplement/alpha-lipoic-acid
10. National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 91820207, Adenosylcobalamin. Retrieved September 13, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Adenosylcobalamin.
11. Pacheco, D. (2024, January 18). Sleep vitamins. Sleep Foundation. https://www.sleepfoundation.org/sleep-aids/vitamins-for-sleep
12. Qiang F. (2015). Effect of Malate-oligosaccharide Solution on Antioxidant Capacity of Endurance Athletes. The open biomedical engineering journal, 9, 326–329.
13. Rabanal-Ruiz, Y., Llanos-González, E., & Alcain, F. J. (2021). The Use of Coenzyme Q10 in Cardiovascular Diseases. Antioxidants (Basel, Switzerland), 10(5), 755. https://doi.org/10.3390/antiox10050755
14. Ramezanpour Ahangar E, Annamaraju P. Hydroxocobalamin. [Updated 2023 May 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557632/
15. Reuter, S., Gupta, S. C., Chaturvedi, M. M., & Aggarwal, B. B. (2010). Oxidative stress, inflammation, and cancer: how are they linked?. Free radical biology & medicine, 49(11), 1603–1616. https://doi.org/10.1016/j.freeradbiomed.2010.09.006
16. Satomi, S., Takahashi, S., Yoshida, K., Shimizu, S., Inoue, T., Takara, T., & Suganuma, H. (2022). Effects of broccoli sprout supplements enriched in glucoraphanin on liver functions in healthy middle-aged adults with high-normal serum hepatic biomarkers: A randomized controlled trial. Frontiers in nutrition, 9, 1077271. https://doi.org/10.3389/fnut.2022.1077271
17. Souza, A. C. R., Vasconcelos, A. R., Dias, D. D., Komoni, G., & Name, J. J. (2023). The Integral Role of Magnesium in Muscle Integrity and Aging: A Comprehensive Review. Nutrients, 15(24), 5127. https://doi.org/10.3390/nu15245127
18. Talbott, S. M., Talbott, J. A., & Pugh, M. (2013). Effect of Magnolia officinalis and Phellodendron amurense (Relora®) on cortisol and psychological mood state in moderately stressed subjects. Journal of the International Society of Sports Nutrition, 10(1), 37–37. https://doi.org/10.1186/1550-2783-10-37
19. Tenório, M. C. D. S., Graciliano, N. G., Moura, F. A., Oliveira, A. C. M., & Goulart, M. O. F. (2021). N-Acetylcysteine (NAC): Impacts on Human Health. Antioxidants (Basel, Switzerland), 10(6), 967. https://doi.org/10.3390/antiox10060967
20. Watson, S. (2023b, September 20). Resveratrol supplements: Side effects and benefits. WebMD. https://www.webmd.com/heart-disease/resveratrol-supplements
21. WebMD. (n.d.). Riboflavin: Overview, uses, side effects, precautions, interactions, dosing and reviews. WebMD. https://www.webmd.com/vitamins/ai/ingredientmono-957/riboflavin
22. WebMD. (n.d.-b). Vitamin B1 (thiamine): Foods and Health Benefits. WebMD. https://www.webmd.com/vitamins-and-supplements/health-benefits-of-vitamin-b-1
23. Zhang, Y., Xun, P., Wang, R., Mao, L., & He, K. (2017). Can Magnesium Enhance Exercise Performance?. Nutrients, 9(9), 946. https://doi.org/10.3390/nu9090946
    24. https://doi.org/10.2174/1874120701509010326 (Retraction published Open Biomed Eng J. 2018 Sep 11;12:91. doi: 10.2174/1874120701812010091)